Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Actinonin-mediated apoptosis begins in the mitochondria. (a) Actinonin (15 μM) causes mitochondrial membrane depolarization in Ramos cells as measured by JC1 dye beginning by 2 h. (b) Inhibition of mitochondrial protein translation begins at 4 h as shown by incorporation of 35S (top) and densitometric measurement (bottom) of the same (c) Caspase-3/7 activation begins at 6 h
