Table 1. The cytotoxicity effect of SKLB-163 on tumor cells.
| Tumor cell line | Cell type | IC50 (μM) (mean±S.D.) |
|---|---|---|
| A375 | Human melanoma cell line | 1.82±0.25 |
| SPC-A1 | Human lung adenocarcinoma cell line | 3.89±0.64 |
| SW620 | Human colorectal cancer cell line | 5.12±0.98 |
| Hela | Human cervical cancer cell line | 5.13±1.09 |
| PC-3 | Human prostate cancer cell line | 6.58±1.05 |
Each cell line was treated with various concentrations (0–20 μM) of SKLB-163 for 48 h, respectively. Cell viability was detected by MTT assay. Data are expressed as the mean±S.D. from three experiments