Table 2. pdr-1 is not involved in the execution of apoptosis.
| Genotype | Extra cells±s.d. | n | P-value |
|---|---|---|---|
| N2 | 0.1±0.2 | 15 | — |
| pdr-1(lg103) | 0.1±0.2 | 15 | — |
| ced-3(n717) | 8±0.4 | 15 | — |
| ced-3(n717);pdr-1(lg103) | 8±0.6 | 35 | 0.711 to ced-3(n717) |
| ced-3(n2438) | 2.3±0.1 | 13 | — |
| ced-3(n2438);pdr-1(lg103) | 1.9±0.2 | 35 | 0.463 to ced-3(n2438) |
pdr-1 does not affect the execution of apoptosis. Third larval stage (L3) animals were anesthetized and viewed using DIC microscopy. The number of extra cell nuclei in the anterior pharynx (pro- and metacorpus) was counted. Alleles used were as follows: ced-3(n717), ced-3(n2438) and pdr-1(lg103). All data are means±s.d. (statistics: paired t-test; two-tailed, unequal variances)