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CcrM is a cell cycle–regulated DNA methyltransferase in C. crescentus. Upper panel: schematic of the C. crescentus cell cycle, showing the differentiation of a swarmer cell (SW) into a stalked cell (ST), which then turns into a pre-divisional cell (PD). Lower panel: schematic showing the changes in the methylation state of GANTC motifs on the chromosome as a function of chromosome replication and cell cycle progression.
