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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: J Neuroimmune Pharmacol. 2014 Feb 8;9(2):102–116. doi: 10.1007/s11481-013-9520-2

Figure 1. The changing face of HIV epidemic as patients age.

Figure 1

The average age of HIV infected people has increased dramatically. A. The percentage of autopsies performed on HIV-infected individuals over the age of 50 has increased from less than 10% in the 80’s to over 30% at present. B. Mechanisms that lead to HAND in individuals under 50 are exacerbated in individuals over 50 and furthermore after years of chronic neuroinflammation. Neurotoxins, inflammation and oxidative stress combined with normal aging processes may cause increased HAND in aged HIV patients.