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. Author manuscript; available in PMC: 2014 Apr 2.
Published in final edited form as: J Neuroimmune Pharmacol. 2011 Aug 9;6(4):551–565. doi: 10.1007/s11481-011-9303-6

Figure 2. Morphine potentiates bacterial burdens in organs and blood of two strains of mice.

Figure 2

Figure 2

Mice were implanted with either a morphine pellet or a placebo pellet 48 hours before i.p. infection. Panel A: C57BL/6 mice (0.1 LD50 dose, A. baumannii, strain 5798, 8.2 × 105 CFU) or Panel B: C3HeB/FeJ mice (0.2 LD50 dose, A. baumannii, strain 4502, 7.2 × 105 CFU). Organs and blood were harvested at 12 hours post-infection for necropsy. Points represent individual animals. Lines are median values for bacterial burdens. Symbols on the X-axis represent animals whose Acinetobacter burden was below the detectable limit of 30 CFU/0.1gram tissue or 1 CFU/0.1ml blood.