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. Author manuscript; available in PMC: 2014 Apr 2.
Published in final edited form as: J Alzheimers Dis. 2014;40(2):359–373. doi: 10.3233/JAD-131913

Figure 3.

Figure 3

Asiaticoside and madecassoside are present in CAW but not protective against Aβ toxicity in MC65 cells. A) Asiaticoside (AS) and madecassoside (MS) were detected by HRMS and their relative percent composition were determined by HPLC-UV. Asiatic and madecassic acid were not detectable (n.d.) in CAW. B) Dose ranges spanning the concentration of AS and MS present in 100ug/mL CAW were tested in MC65 cells for their ability to attenuate Aβ-induced cell death following tetracycline withdrawal. Neither compound offered any protection at any dose tested; ***p<0.01 relative to Tet+. n=24 per treatment condition.