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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Rev Med Virol. 2013 Nov 14;24(1):55–70. doi: 10.1002/rmv.1773

Table 1. Expression of different types of FcγR on innate cells and B cells and its proposed effect in the immune response against pathogens.

The right hand column, separated by a dated vertical line, indicates inhibitory receptors.

Type FcγRI FcγRIIA FcγRIIC FcγRIIIA FcγRIIIB FcγRIIB
Expression Monocyte
Macrophage
Dendritic cell
Neutrophil
Eosinophil
Mast cell1
Monocyte
Macrophage
Dendritic cell
Neutrophil
Basophil
Eosinophil
NKcell Monocyte
Macrophage
Dendritic cell
NK cell
Mast cell
Neutrophil
Eosinophil1
Monocyte
Macrophage
Dendritic cell
Neutrophil
Basophil
Mast cell
NK cell
B cell
Effect Phagocytosis
Cytokine release
ADE2
Degranulation3
Complement activation4
Phagocytosis
Cytokine release
ADE2
ADCC5
Cytokine release
ADCC5 6
Phagocytosis
Cytokine release
Cross-talk TLR-4
Complement activation4
ADCC5
Phagocytosis
Chemoattractants
Cross-talk TLR-4
Degranulation3
ADCC
Reduced phagocytosis
Reduced TLR sigaling
Reduced proliferation
Apoptosis7
1

Upon stimulation with IFN-γ;

2

Antibody-dependent enhancement of disease;

3

Mast cells;

4

In mice models;

5

Antibody-dependent cellular toxicity;

6

Interaction with FcγRIII;

7

B cells