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. Author manuscript; available in PMC: 2014 Apr 2.
Published in final edited form as: Mol Microbiol. 2008 Apr 11;68(6):1428–1437. doi: 10.1111/j.1365-2958.2008.06245.x

Figure 6. The common precursor vs. a linear model of cryptococcal prostaglandin synthesis.

Figure 6

Panel A depicts the common precursor model of prostaglandin synthesis where cyclooxygenase enzymes act on free arachidonic acid to produce PGH2, which then serves as the common substrate for the individual prostaglandin synthases. Panel B depicts the proposed linear model of cryptococcal prostaglandin synthesis, where each step is dependent upon the product of the step before. Dashed arrows indicate other possible synthetic routes.