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. 2014 Apr 2;9(4):e93706. doi: 10.1371/journal.pone.0093706

Figure 9. fMRI study of the optogenetic tactile sense (OTS).

Figure 9

A, System setup. B, The block design of the stimulation paradigm. C, Coronal T1 image of the rat brain. The region selected for getting the tangential images is shown by a magenta stripe. D, Sequential images indicating the change of BOLD signal (ΔBOLD) induced by 16-whisker photostimulation. The time from onset of the first light pulse is indicated; 0 s (D1), 5 s (D2), 10 s (D3), 15 s (D4) and 20 s (D5). E, Sequential images indicating theΔBOLD induced by a single D3 whisker photostimulation. The time from onset of the first light pulse is indicated; 0 s (E1), 5 s (E2), 10 s (E3), 15 s (E4) and 20 s (E5). Scale bars indicate 2 mm.