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. 2014 Apr 2;9(4):e93746. doi: 10.1371/journal.pone.0093746

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© 2014 Jun et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Pancreata were stained for insulin and showed positive staining in the β-cells of (A) mGlp-1r, (B) hGLP-1R, and (C) Glp-1r^−/− islets. FLAG staining was also performed and (E) hGLP-1R islets stained positive for FLAG with none detected in (D) mGlp-1r and (F) Glp-1r^−/− islets.