Skip to main content
. 2014 Apr 2;9(4):e93788. doi: 10.1371/journal.pone.0093788

Figure 1. Intravitreal injection of IGFBP-3 plasmid increases IGFBP-3, while reducing TNFα levels.

Figure 1

For all studies, groups are control (ctrl), diabetic (Diabetic), Diabetic +IGFBP-3 NB (Diab +BP3), Diabetic +CMV (Diab+CMV), Diabetic+IGFBP-3 NB left eye (Diab+BP3 contra) and Diabetic+CMV left eye (Diab+CMV Contra). Panel A shows ELISA results for IGFBP-3 demonstrating that the plasmid injection did significantly increase IGFBP-3 levels. Panel B demonstrates that intravitreal injection of IGFBP-3 NB significantly reduced TNFα levels. *P<0.05 vs ctrl. #P<0.05 vs. Diabetic only, $P<0.05 vs. Diab+BP3. N = 5 for all groups Data are mean ± SEM.