Table 2. Interaction of residues with other protein subunits of Complex I as determined by the predicted African elephant protein structure.
Mutation | Binding Residue | Interacting Subunit(s) | Relative Accessible Surface Area (%) |
ND1, 49 | + | ND2, ND3 | 30.1 |
ND4, 15 | + | ND2 | 0.2 |
ND5, 20 | − | − | 42.2 |
ND5, 21 | − | − | 0.8 |
ND6, 43 | + | ND2, ND3, ND4L | 0.1 |
ND6, 45 | + | ND2, ND4L | 54.0 |