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. Author manuscript; available in PMC: 2014 Jul 30.
Published in final edited form as: Nature. 2014 Jan 30;505(7485):706–709. doi: 10.1038/nature12946

Figure 1. PARS reveals the landscape of human RNA structure.

Figure 1

a, Experimental overview. b, Pie chart showing the distribution of structure-probed RNAs with a coverage of at least one read per base. c, High (red arrows) and low (green arrows) PARS scores were mapped onto the secondary structure of snoRNA74A. d, PARS score (Top: renatured transcripts; Middle: native deproteinized transcripts) and GC content (Bottom) across the 5’UTR, the coding region, and the 3’UTR, averaged across all transcripts, aligned by translational start and stop sites. (averaged regions are shaded in pink, blue and green for 5’UTR, CDS and 3’UTR respectively).