Skip to main content
. Author manuscript; available in PMC: 2014 Jul 30.
Published in final edited form as: Nature. 2014 Jan 30;505(7485):706–709. doi: 10.1038/nature12946

Figure 2. RSS signatures of post-transcriptional regulation.

Figure 2

a, Average PARS score and GC content across transcript exon-exon junctions. b, Average PARS score (Top) and PARS score difference (Bottom) across miRNA sites for AGO-bound (red) vs. non-AGO-bound sites (grey). Structurally different regions are in beige and light grey. c, AGO-iCLIP binding for single vs. double-stranded miRNA target sites. d, P-value for differential AGO-iCLIP binding (t-test, p=0.05 in grey). e, Observed vs. expected AGO binding (p-value, chi-square test). f, Expression changes of mRNAs with accessible and inaccessible miR142 (left) or miR148 (right) sites, upon miRNA over-expression (Wilcoxon Rank sum test).