Table 2.

Pharmacokinetics of hCG After SC vs IM Injection in Normal and Obese Women^a

	Normal Weight (n = 11)			Obese (n = 11)
	SC	IM	P Valueb	SC	IM	P Valueb
Tmax by 12 h, %	54.6	45.5	>.99	18.2	81.8	.008
Cmax, mIU/mL	142 (115–192)	291 (225–380)	.002	89 (58–123)	436 (246–526)	.001
AUC, mIU/h·mL	4152 (3410–5395)	9586 (5945–11 625)	.003	2352 (1593–3655)	13327 (7736–14 863)	.001
Average concentration, mIU/mL	72 (59–96)	189 (96–220)	.003	34 (25–55)	277 (168–344)	.001

^aProportion of women who reached Tmax by the 12-hour time point is expressed as a percentage; all other data are expressed as median (interquartile range).

^bP values comparing responses within woman after an im vs sc injection of hCG were calculated using Wilcoxon signed rank tests.