Table 5.
Ovarian Steroids After Subcutaneous hCG Injection in Normal and Obese Womena
| Analyte | Time Point (hours) | Normal (n = 11) | Obese (n = 11) | P Valueb |
|---|---|---|---|---|
| Estradiol, pg/mL | 0 | 107.5 (55.7–205.3) | 79.2 (60.8–101.4) | .11 |
| 36 | 67.4 (58.5–106.2) | 74.7 (71.5–132.2) | ||
| P valuec | .16 | .03 | ||
| Progesterone, ng/mL | 0 | 0.4 (0.2–0.5) | 0.8 (0.4–2.4) | .18 |
| 36 | 0.5 (0.3–0.9) | 0.6 (0.4–6.1) | ||
| P valuec | .08 | .10 | ||
| T, ng/dL | 0 | 31.8 (17.7–45.1) | 35.8 (21.0–42.6) | .32 |
| 36 | 38.5 (33.6–43.4) | 41.6 (26.0–49.9) | ||
| P valuec | .31 | .04 | ||
| SHBG, nmol/L | 0 | 58.8 (43.6–102.4) | 47.7 (27.0–68.9) | .03 |
| 36 | 75.2 (52.4–113.4) | 51.7 (28.5–78.0) | ||
| P valuec | .06 | .02 | ||
| 17-OHP, ng/dL | 0 | 25.0 (20.0–47.5) | 31.0 (12.5–43.5) | .71 |
| 36 | 89.0 (57.0–121.0) | 78.0 (64.0–156.0) | ||
| P valuec | .001 | .001 | ||
| DHEA, ng/dL | 0 | 92.0 (66.0–181.5) | 204.0 (129.5–267.0) | .24 |
| 36 | 124.5 (65.0–151.5) | 158.0 (107.0–193.5) | ||
| P valuec | .64 | .03 |
a
Results are expressed as median (interquartile range).
b
P values comparing normal with obese women were calculated using Wilcoxon rank sum (Mann-Whitney U) tests.
c
P values comparing responses from baseline with 36 hours within a weight class were calculated using Wilcoxon signed rank tests.