Table 4.
Multivariate Models of Placental CYP27B1 and CYP24A1 Expression
| R2 (Model) | β | P Value | |
|---|---|---|---|
| CYP27B1 | |||
| CYP27B1 protein (n = 60) | 0.22 | .0024 | |
| Midgestation 25(OH)D | 0.0089 | .0079 | |
| Midgestation IL-6 | 0.039 | .0222 | |
| Placental VDR protein expression | −0.10 | .0283 | |
| CYP27B1 mRNA (n = 47) | 0.32 | .0007 | |
| Midgestation 1,25(OH)2D | 0.020 | .0003 | |
| Midgestation serum calcium | −1.4 | .0172 | |
| Delivery estradiol | −0.00014 | .0208 | |
| CYP24A1 | |||
| CYP24A1 protein (n = 63) | 0.23 | .0003 | |
| Placental CYP27B1 protein | 0.80 | .0031 | |
| Cord OPG | −0.00023 | .0065 | |
| CYP24A1 mRNA (n = 46) | 0.23 | .0040 | |
| Delivery serum leptin | −0.011 | .0065 | |
| Cord IL-6 | −0.15 | .0240 |