Table 1.
Serum biochemical parameters in control and different treated rat groups
| Animal groups | Control | GSPE | Fish oil | Cisplatin | GSPE + Cisplatin | Fish oil + Cisplatin | |
|---|---|---|---|---|---|---|---|
| Creatinine (mg/dl) | Mean ± SE | 1.08 ± 0.043a | 1.08 ± 0.051a | 1.21 ± 0.078a | 6.26 ± 0.44b | 3.96 ± 0.27d | 4.54 ± 0.40d |
| Urea (mg/dl) | Mean ± SE | 63.45 ± 2.28a | 60.36 ± 3.04a | 62.25 ± 2.81a | 123.35 ± 2.73b | 109.13 ± 3.30d | 103.83 ± 3.06d |
| Uric acid (mg/dl) | Mean ± SE | 1.50 ± 0.15a | 1.71 ± 0.19a | 1.24 ± 0.08a | 3.02 ± 0.27b | 1.88 ± 0.12a | 1.99 ± 0.29a |
| Na (mmol/L) | Mean ± SE | 147.13 ± 2.73a | 168.61 ± 6.77b | 162.44 ± 7.85a,b | 84.72 ± 3.36c | 120.80 ± 6.30d | 120.64 ± 8.32d |
| K (mmol/L) | Mean ± SE | 6.44 ± 0.31a | 6.59 ± 0.35a | 5.95 ± 0.28a | 4.33 ± 0.41b | 6.05 ± 0.12a | 4.65 ± 0.25b |
| Ca (mg/dl) | Mean ± SE | 5.01 ± 0.14a | 5.25 ± 0.36a | 4.72 ± 0.17a | 3.35 ± 0.29b | 4.16 ± 0.21c | 4.01 ± 0.35d |
GSPE Grape seed proanthcyanidin extract
Data are expressed as mean ± SE of 6 rats. Within each row, means with different superscript (a, b, c, d, e) were significantly different at p < 0.05, whereas means superscripts with the same letters mean that there is no significant difference at (p > 0.05)