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. 2004 Mar 24;101(15):5328–5335. doi: 10.1073/pnas.0400053101

Table 3. Percentages of TUNEL positive cells in cultured cells.

Treatment options (group)
Time after treatment, days ATRA (1) As2O3 (2) ATRA/As2O3 (3)
Cultured NB4 cells
    2 1.5 ± 1.0 1.5 ± 1.0 2.0 ± 0.9
    4 2.0 ± 1.0 2.5 ± 1.3 3.5 ± 2.3
    6 2.0 ± 1.5 8.5 ± 2.6* 14.5 ± 2.6†
    8 4.5 ± 0.9 12.0 ± 2.2 20.5 ± 4.8‡
    10 5.0 ± 1.7 14.5 ± 3.1§ 28.0 ± 5.2∥
Cultured primary APL cells
    2 1.0 ± 0.5 1.0 ± 0.5 1.5 ± 0.9
    4 1.3 ± 1.0 2.2 ± 1.2 3.8 ± 2.0
    6 2.2 ± 0.8 5.8 ± 1.5 11.3 ± 3.5**
    8 3.8 ± 0.8 8.9 ± 2.5 17.2 ± 3.4††
    10 4.0 ± 1.3 12.7 ± 2.4‡‡ 24.3 ± 5.7§§¶¶
*

, P = 0.025 vs. group 1; †, P = 0.001 vs. group 1; ‡, P = 0.001 vs. group 1; §, P = 0.024 vs. group 1; ¶, P < 0.0001 vs. group 1; ∥, P = 0.02 vs. group 2; **, P = 0.01 vs. group 1; ††, P = 0.002 vs. group 1; ‡‡, P = 0.026 vs. group 1; §§, P < 0.0001 vs. group 1; ¶¶, P = 0.035 vs. group 2.