Table 3.
Circulating levels of the IL-6 family members in STEMI patients (n = 1028), related to patient characteristics.
| IL-6 pg/mL | sgp130 ng/mL | sIL-6R ng/mL | CRP mg/L | |
|---|---|---|---|---|
| Female | 19.4 (13.3, 31.4) | 240 (218, 264) | 39,1 (30.9, 46.9) | 16.3 (8.2, 38.3) |
| Male | 18.7 (14.1, 29.8) | 240 (219, 259) | 39.4 (31.2, 47.8) | 13.0 (6.9, 31.1) |
| p-Value | 0.7 | 0.09 | 0.9 | 0.09 |
| No smokers | 18.5 (14.1, 29.3) | 244 (222, 265) | 39.3 (31.5, 47.7) | 12.0 (6.2, 34.2) |
| Smokers | 19.1 (13.8, 30.2) | 238 (217, 258) | 39.2 (30.8, 47.5) | 14.2 (7.1, 31.5) |
| p-Value | 0.5 | 0.005 | 0.7 | 0.2 |
| Low TnT maxa | 18.0 (13.2, 26.2) | 240 (217, 259) | 39.7 (30.9, 47.8) | 11.7 (6.2, 26.5) |
| High TnT max | 25.0 (17.3, 36.5) | 240 (222, 265) | 38.6 (31.3, 47.3) | 22.1 (10.5, 49.5) |
| p-Value | <0.001 | 0.2 | 0.8 | <0.001 |
| Low NT-proBNPb | 18.1 (13.0, 26.8) | 238 (218, 258) | 39.4 (31.1, 48.1) | 11.6 (6.0, 23.3) |
| High NT-proBNP | 24.3 (17.4, 34.5) | 246 (221, 268) | 38.7 (30.4, 46.3) | 31.1 (11.6, 82.0) |
| p-Value | <0.001 | 0.007 | 0.2 | <0.001 |
| LVEF <40% | 29.0 (17.9, 37.5) | 240 (223, 265) | 37.9 (29.5, 49.1) | 36.1 (4.11, 9.5) |
| LVEF =40% | 18.6 (13.3, 29.0) | 239 (218, 259) | 39.3 (30.9, 47.3) | 13.3 (6.8, 29.4) |
| p-Value | <0.001 | 0.2 | 0.8 | <0.001 |
| No diabetics | 18.7 (14.1, 29.7) | 239 (218, 259) | 39.2 (31.2, 47.5) | 13.1 (7.0, 31.0) |
| Diabetics | 19.1 (12.7, 33.7) | 247 (226, 270) | 39.7 (30.6, 47.8) | 16.6 (7.5, 58.5) |
| p-Value | 0.5 | 0.002 | 1.0 | 0.04 |
| Low HbA1cc | 18.6 (14.0, 29.0) | 238 (217, 258) | 39.1 (30.9, 47.4) | 13.1 (6.9, 30.7) |
| High HbA1c | 20.0 (13.9, 33.3) | 246 (229, 273) | 40.6 (31.7, 47.9) | 17.0 (7.8, 49.6) |
| p-Value | 0.056 | <0.001 | 0.4 | 0.03 |
| Low admission glucosed | 18.7 (13.9, 29.2) | 239 (218, 260) | 39.2 (31.2, 47.6) | 12.8 (6.9, 29.3) |
| High admission glucose | 20.6 (15.6, 34.8) | 246 (224, 273) | 39.1 (30.3, 49.1) | 23.3 (10.2, 68.9) |
| p-Value | 0.016 | 0.02 | 0.7 | <0.001 |
| Low fasting glucosee | 18.7 (13.9, 29.0) | 239 (218, 259) | 39.2 (30.9, 47.6) | 12.7 (6.9, 29.2) |
| High fasting glucose | 19.7 (14.3, 33.8) | 243 (220, 270) | 39.3 (31.7, 47.2) | 18.3 (8.4, 52.8) |
| p-Value | 0.07 | 0.05 | 0.7 | <0.001 |
Medians (25,75 percentiles) are given.
a
TnT max low <7140 ng/L and high =7140 ng/L.
b
Low NT-proBNP <122 ng/L and high =122 ng/L.
c
Low HbA1c <6.5% and high =6.5%.
d
Low admission glucose <11.1 mmol/L and high =11.1 mmol/L.
e
Low fasting glucose <7.0 mmol/L and high =7.0 mmol/L.