Table 2.
Correlations between biomarkers in CSF and MMSE in patients with AD and controls combined
| CSF Aβ42 | CSF Tau | CSF P-Tau | MMSE | |
|---|---|---|---|---|
| CSF IGF-I |
0.253a |
0.191 |
0.116 |
-0.005 |
| CSF IGF-II |
0.058 |
0.161 |
0.155 |
-0.178a |
| CSF IGFBP-2 |
0.034 |
0.463b |
0.374b |
-0.250b |
| CSF IGFBP-3 |
0.060 |
0.308b |
0.266a |
-0.143 |
| MMSE | 0.374b | -0.442b | -0.567b | 1.000 |
Numbers are Spearman correlation coefficients (rs). ap < 0.05; bp < 0.005. Abbreviations: CSF cerebrospinal fluid, IGF insulin growth factor, IGFBP insulin growth factor binding protein, MMSE Mini-Mental State Examination.