Table 3.
Correlations between biomarkers in CSF and MMSE in patients with AD
| CSF Aβ42 | CSF Tau | CSF P-Tau | MMSE | |
|---|---|---|---|---|
| CSF IGF-I |
0.220 |
0.146 |
0.253a |
0.096 |
| CSF IGF-II |
0.155 |
0.050 |
0.183 |
0.034 |
| CSF IGFBP-2 |
0.177 |
0.380b |
0.398b |
-0.075 |
| CSF IGFBP-3 |
0.294 |
0.212 |
0.322a |
0.070 |
| MMSE | -0.079 | -0.208 | -0.100 | 1.000 |
Numbers are Spearman correlation coefficients (rs). ap < 0.05; bp < 0.005. Abbreviations: CSF cerebrospinal fluid, IGF insulin growth factor, IGFBP insulin growth factor binding protein, MMSE Mini-Mental State Examination.