Table 3.
RR for asthma hospitalization in childhood according to gestational age and estimated fetal growth
| Fetal development variables | Cases | Cumulative incidence (%) | Crude RR | Adjusted RR* (95% CI) |
|---|---|---|---|---|
| 22-28 weeks |
|
|
|
|
| SGA |
180 |
9.09 |
1.14 |
1.02 (0.86-1.21) |
| AGA |
527 |
7.96 |
1 |
1 (ref) |
| LGA |
30 |
5.43 |
0.71 |
0.71 (0.46-1.11) |
| Z-score per decreased of SD |
- |
- |
1.04 |
1.02 (0.99-1.04) |
| 29-32 weeks |
|
|
|
|
| SGA |
359 |
6.15 |
1.20 |
1.07 (0.94-1.22) |
| AGA |
1,010 |
5.05 |
1 |
1 (ref) |
| LGA |
47 |
2.96 |
0.58 |
0.60 (0.43-0.85) |
| Z-score per decreased of SD |
- |
- |
1.06 |
1.04 (1.02-1.07) |
| 33-36 weeks |
|
|
|
|
| SGA |
675 |
4.27 |
1.26 |
1.06 (0.97-1.17) |
| AGA |
5,409 |
3.43 |
1 |
1 (ref) |
| LGA |
387 |
3.41 |
0.99 |
0.94 (0.84-1.05) |
| Z-score per decreased of SD |
- |
- |
1.05 |
1.03 (1.01-1.04) |
| 37-38 weeks |
|
|
|
|
| SGA |
860 |
3.56 |
1.22 |
1.15 (1.07-1.24) |
| AGA |
20,735 |
2.93 |
1 |
1 (ref) |
| LGA |
1,467 |
3.43 |
1.17 |
1.03 (0.97-1.09) |
| Z-score per decreased of SD |
- |
- |
0.99 |
1.02 (1.01-1.03) |
| 39-41 weeks |
|
|
|
|
| SGA |
2,349 |
3.01 |
1.12 |
1.12 (1.07-1.17) |
| AGA |
85,611 |
2.71 |
1 |
1 (ref) |
| LGA |
3,095 |
3.06 |
1.13 |
1.06 (1.02-1.10) |
| Z-score per decreased of SD |
- |
- |
0.99 |
1.02 (1.01-1.03) |
| 42-45 weeks |
|
|
|
|
| SGA |
455 |
2.51 |
1.07 |
1.11 (0.98-1.25) |
| AGA |
8,449 |
2.36 |
1 |
1 (ref) |
| LGA |
138 |
2.83 |
1.20 |
1.15 (0.95-1.40) |
| Z-score per decreased of SD | - | - | 1.00 | 1.02 (0.99-1.05) |
*Adjusted for country of residence, maternal age at delivery, maternal social status, parity, mode of delivery, sex of the child, calendar year of birth and family history of asthma.