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Renal histology of SIOD patient. Light microscopy images (A, B) showing larger glomerular volume, with a sclerotic lesion of the glomerular tuft. The remaining part of the glomerulus shows focal and segmental matrix increase and mesangial proliferation. Diffuse tubular atrophy and rare arteriolar ialinosis are also present (A: PAS staining, B: Masson’s Trichrome stain; ×400).
