Table 2. Scope of O-nitroso aldol reaction.

Entry	4		Yield, %*	5/7†	ee of 5, %‡	(Conf.)§
1		4a	94	>99/-	>99	(R)
2		4b	87	>99/-	>99
3		4c	97	>99/-	99
4		4d	95	>99/-	>99
5¶		4e	75	72/28	>99
6**		4f	67∥	>99/-	98	(R)
7††		4g	65∥	>99/-	98
8**		4h	69∥	>99/-	98

Reactions were conducted with 5 mol % of 3f, 1.0 eq of nitrosobenzene, and 3 eq of 4 in DMSO at rt.

^*Isolated yield.

^†Determined by yield of each isolated isomer.

^‡Determined by HPLC (Supporting Text).

^§Determined after conversion to the corresponding diol (Supporting Text).

^¶Reaction was conducted with 20 mol % of 3f in DMSO at rt.

^∥Determined by isolated yield of corresponding primary alcohol obtained after reduction of product.

^**Reactions were conducted with 10 mol % of 3f in MeCN at rt.

^††Reaction was conducted with 20 mol % of 3f in MeCN at rt.