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. 2013 Nov 23;20(2):453–459. doi: 10.1007/s12253-013-9716-z

Table 1.

Functional grouping of 84 obesity-related genes assessed by the quantitative PCR array (Human Obesity RT2 Profiler PCR Array; SABioscience, Frederick, MD, USA)

Orexigenic genes
 Neuropeptides and receptors: ADRA2B, AGRP, CNR1, GAL, GALR1, MCHR1 (GPR24), HCRT, HCRTR1, NPY, NPY1R, NR3C1 (GRL), OPRK1, OPRM1.
 Gut hormone and receptor: GHRL (Ghrelin / Obestatin), GHSR.
Anorectic genes
 Neuropeptides and receptors: ATRN (Attractin), BDNF, BRS3, CALCA, CALCR, CARTPT (CART), CNTFR, CRHR1, DRD1, DRD2, GH1, GH2, GHR, NMUR1 (GPR66), GRP, GRPR, HRH1, HTR2C, IL1A, IL1B, IL1R1, IL6, IL6R, MC3R, NMB, NMBR, NMU, NTRK2, NTS, NTSR1, PRLHR (GPR10), POMC, SORT1, TRH, UCN, ZFP91.
 Gut hormones and receptors: APOA4, CCK, CCKAR, GLP1R, PYY.
 Adipocyte-derived peptides and receptors: LEP (Leptin), LEPR, TNF.
 Pancreas derived peptides and receptors: CALCR, CLPS, GCG, GCGR, GLP1R, IAPP, INS, INSR, RAMP3, SST, SSTR2.
Genes related to energy expenditure
 Adipocyte-derived peptides and receptors: ADIPOQ (ACRP30), ADIPOR1, ADIPOR2, ADRB1, C3, PPARA, PPARG, PPARGC1A, PTPN1, UCP1.
 CNS-derived peptides and receptors: ADCYAP1, ADCYAP1R1, CPD, CPE, SIGMAR1, THRB.

Genes rendered in italics had mean expression over threefold upregulated (ZFP91 and IL1R1) or downregulated (TNF) in BPH samples relative to control prostate tissues (each group n = 3)