Table 1.
Orexigenic genes | |
Neuropeptides and receptors: | ADRA2B, AGRP, CNR1, GAL, GALR1, MCHR1 (GPR24), HCRT, HCRTR1, NPY, NPY1R, NR3C1 (GRL), OPRK1, OPRM1. |
Gut hormone and receptor: | GHRL (Ghrelin / Obestatin), GHSR. |
Anorectic genes | |
Neuropeptides and receptors: | ATRN (Attractin), BDNF, BRS3, CALCA, CALCR, CARTPT (CART), CNTFR, CRHR1, DRD1, DRD2, GH1, GH2, GHR, NMUR1 (GPR66), GRP, GRPR, HRH1, HTR2C, IL1A, IL1B, IL1R1, IL6, IL6R, MC3R, NMB, NMBR, NMU, NTRK2, NTS, NTSR1, PRLHR (GPR10), POMC, SORT1, TRH, UCN, ZFP91. |
Gut hormones and receptors: | APOA4, CCK, CCKAR, GLP1R, PYY. |
Adipocyte-derived peptides and receptors: | LEP (Leptin), LEPR, TNF. |
Pancreas derived peptides and receptors: | CALCR, CLPS, GCG, GCGR, GLP1R, IAPP, INS, INSR, RAMP3, SST, SSTR2. |
Genes related to energy expenditure | |
Adipocyte-derived peptides and receptors: | ADIPOQ (ACRP30), ADIPOR1, ADIPOR2, ADRB1, C3, PPARA, PPARG, PPARGC1A, PTPN1, UCP1. |
CNS-derived peptides and receptors: | ADCYAP1, ADCYAP1R1, CPD, CPE, SIGMAR1, THRB. |
Genes rendered in italics had mean expression over threefold upregulated (ZFP91 and IL1R1) or downregulated (TNF) in BPH samples relative to control prostate tissues (each group n = 3)