Table 2.
All subjects |
Hypocapnia |
Normocapnia |
Hypercapnia |
|
---|---|---|---|---|
n = 75 | n = 11 | n = 47 | n = 17 | |
Initial prescribed ventilation Settings |
|
|
|
|
FiO2‡ (%) |
100 (80 to 100) |
100 (70 to 100) |
100 (68 to 100) |
100 (100 to 100) |
PEEP (cmH2O) |
5 (5 to 5) |
5 (5 to 5) |
5 (5 to 5) |
5 (5 to 5) |
Tidal Volume (mL/kg) |
7 (7 to 8) |
8 (7 to 8) |
7 (7 to 8) |
7 (6 to 7) |
Respiratory rate (breaths/minute) |
14 (14 to 16) |
14 (14 to 21) |
14 (14 to 16) |
14 (12 to 14) |
Post-resuscitation shocka (n (%)) |
69 (92) |
11 (100) |
41 (87) |
17 (100) |
Metabolic acidosisb (n (%)) |
49 (65) |
9 (82) |
27 (57) |
13 (76) |
pH |
7.24 |
7.27 |
7.29 |
7.04 |
(7.07 to 7.33) |
(7.05 to 7.34) |
(7.15 to 7.37) |
(6.98 to 7.13) |
|
Bicarbonate (mmol/L) | 18 (13 to 23) | 12 (7 to 18) | 19 (14 to 23) | 18 (14 to 23) |
aDefined as systolic blood pressure < 100 mmHg or vasopressor support required to maintain systolic blood pressure > 100 mmHg during the first 24 hours after return of spontaneous circulation; bDefined as a base deficit ≤ - 6 mmol/L during the first 24 hours after return of spontaneous circulation; ‡FiO2, fraction of inspired oxygen; PEEP, peak end expiratory pressure.