Table 1.
Characteristics of the 25 patients at baseline and at follow up (8 weeks of treatment)
| Variables | Visit 1 (Pre-treatment) | Visit 2 (Post treatment) | p |
|---|---|---|---|
| Age (years) |
59.2 [55.2; 63.2] |
- |
|
| Male gender (%) |
13.0 (52.0%) |
- |
|
| Current smoker |
4.0 (16.0%) |
- |
|
| Hypertension |
19.0 (76.0%) |
- |
|
| Cardiovascular disease |
5.0 (20.0%) |
- |
|
| Ischemic heart disease |
4.0 (16.0%) |
- |
|
| Ischemic stroke |
1.0 (4%) |
- |
|
| Medication |
|
|
|
| ACEI |
10.0 (40.0%) |
- |
|
| β-Adrenergic receptor blocker |
8.0 (32.0%) |
- |
|
| Diuretics |
8.0 (32.0%) |
- |
|
| Calcium channel blocker |
7.0 (28.0%) |
- |
|
| Angiotensin receptor blocker |
4.0 (16.0%) |
- |
|
| Aspirin |
7.0 (28.0%) |
- |
|
| SBP (mmHg) |
149.8 [143.5; 156.1] |
142.7 [137.6; 147.8] |
0.04 |
| DBP (mmHg) |
91.5 [87.4; 95.5] |
87.5 [82.8; 92.2] |
0.02 |
| BMI (kg/m2) |
28.7 [26.6; 34.2]
a
|
28.7 [26.7; 34.0]
a
|
0.79 |
| Waist (cm) |
108.5 [104.0; 113.0] |
110.4 [105.5; 115.3] |
0.06 |
| FPG (mg/dl) |
136.9 [129.0; 144.8] |
137.6 [129.7; 145.5] |
0.82 |
| HbA1c (%) |
6.5 [6.3; 6.8] |
6.5 [6.3; 6.7] |
0.53 |
| Lipids |
|
|
|
| Total cholesterol (mg/dl) |
182.0 [166.0; 220.0]
a
|
168.0 [151.0; 192.5]
a
|
0.01 |
| HDL cholesterol (mg/dl) |
45.0 [40.1; 50.0] |
44.1 [37.7; 50.5] |
0.88 |
| LDL-cholesterol (mg/dl) |
104.0 [93.0; 139.3]
a
|
102.0 [89.1; 125.6]
a
|
0.14 |
| Triglycerides (mg/dl) |
168.6 [140.2; 197.0] |
114.1 [95.4; 132.8] |
<0.001 |
| eGFR (ml/min/1.73 m2) |
107.7 [93.4; 122.0] |
96.8 [82.6; 111.1] |
0.007 |
| TGO (IU/L) |
20.0 [15.5; 25.0]
a
|
22.0 [18.0; 26.0]
a
|
0.10 |
| TGP (IU/L) | 22.0 [17.0; 27.0] a | 24.0 [20.0; 28.0] a | 0.48 |
Data in table are presented as mean [95%CI] for continuous variables, median [1st quartile; 3rd quartile] for variables with abnormal distribution and number (%) for categorical variables; a- abnormal distribution; BMI - body mass index; HbA1c – glycosilated hemoglobin; SBP –systolic blood pressure; DBP – diastolic blood pressure; FPG – fasting plasma glucose; eGFR- estimated glomerular filtration rate.