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. 2014 Feb 28;15:60. doi: 10.1186/1471-2105-15-60

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Copyright © 2014 Huang and Voß; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Folding kinetics of the Spliced Leader RNA from L. collosoma simulated with HIKINETICS. Folding kinetics for the 25 best π_hhishapes plus the open chain ([_]), which was used as the starting structure for this simulation. The simulation was based on the 100 best π_hhishapes and the open chain. The simulation took 253 min using 64 cores of a 4x AMD Opteron 6282SE machine with 512 GB RAM running under openSuSE 12.2. This figure was generated using. '/HiKinetics.rb -i Input/spliced_leader.seq -o Output/spliced_leader -k 100 -t 4’.