Table 7.
Consent processes and understanding of the trial (Household survey)
| |
Site A |
Site B |
Site C |
Total |
|---|---|---|---|---|
| n = 67 (%) | n = 33 (%) | n = 100 (%) | n = 200 (%) | |
|
Main purpose of the trial |
|
|
|
|
| Provide treatment/help to participating children |
32 (47.8) |
18 (54.5) |
71 (71.0) |
121 (60.5) |
| Learn about potential for preventing malaria |
27 (40.3) |
12 (36.4) |
23 (23.0) |
62 (31.0) |
| DK |
3 (4.5) |
1 (3.0) |
3 (3.0) |
7 (3.5) |
| Other activities |
2 (3.0) |
0 |
2 (2.0) |
4 (2.0) |
| Missing/data not clear to code |
3(4.5) |
2 (6.1) |
1 (1.0) |
6 (3.0) |
|
Did all children in the trial get a malaria vaccine? |
|
|
|
|
| Yes |
38 (56.7) |
19 (57.6) |
63 (63.0) |
120 (60.0) |
| No |
12 (17.9) |
6 (18.2) |
11 (11.0) |
29 (14.5) |
| DK |
17 (25.4) |
8 (24.2) |
24 (24.0) |
49 (24.5) |
| Missing data |
0 |
0 |
2 (2.0) |
2 (1.0) |
|
Do you think children who got trial vaccines are still able to get malaria? |
|
|
|
|
| Yes |
10 (14.9) |
5 (15.2) |
15 (15.0) |
30 (15.0) |
| No |
32 (47.8) |
17 (51.5) |
56 (56.0) |
105 (52.5) |
| DK |
25 (37.3) |
11 (33.3) |
28 (28.0) |
64 (32.0) |
| Missing data |
0 (0) |
0 |
1 (1.0) |
1 (0.5) |
|
Would consider participating in future similar trial? |
|
|
|
|
| Agree |
45 (67.2) |
20 (60.6) |
80 (80.0) |
145 (72.5) |
| Not agree |
2 (3.0) |
0 |
0 |
2 (1.0) |
| Indifferent/DKa |
20 (29.9) |
13 (39.4) |
20 (20.0) |
53 (26.5) |
|
Content with decision to enrol your child in the trial? |
|
|
|
|
| Yes |
61 (91.0) |
31 (93.9) |
94 (94.0) |
186 (93.0) |
| No |
4 (6.0) |
0 |
2 (2.0) |
6 (3.0) |
| Indifferent |
2 (3.0) |
2 (6.1) |
4 (4.0) |
8 (4.0) |
|
Most important reasons for enrolling in trial (top five) |
|
|
|
|
| Access to free treatment |
18 (26.9) |
10 (30.3) |
35 (35.0) |
63 (31.5) |
| Access to better and quality services |
9 (13.4) |
6 (18.2) |
25 (25.0) |
40 (20.0) |
| Vaccine beneficial |
12 (17.9) |
5 (15.2) |
13 (13.0) |
30 (15.0) |
| Detailed explanation of the study |
5 (7.5) |
3 (9.1) |
7 (7.0) |
15 (7.5) |
| Previous experience/interaction with KEMRI | 3 (4.5) | 4 (12.1) | 6 (6.0) | 13 (6.5) |
a Here most people reported they would first want to hear more about what the trial would involve at the point of information giving before making their decision.
DK; do not know.