Table 1.
Characteristics and genotype distributions in asthmatics and controlsª
| Asthmatics | Controls | P-value | OR | 95% CI | |
|---|---|---|---|---|---|
| Age (Mean ± SD), years |
7.65 ± 1.916 |
8.27 ± 1.785 |
0.025* |
_ |
_ |
| Sex |
|
|
|
_ |
_ |
| Male |
62 (66%) |
44 (48.9%) |
0.019* |
|
|
| Female |
32 (34%) |
46 (51.1%) |
|
|
|
| Spirometry |
|
|
_ |
_ |
_ |
| FEV1 (%predicted)** |
97 ± 6.2 |
_ |
|
|
|
| FVC (%predicted)*** |
96 ± 8.2 |
|
|
|
|
| Disease severity |
|
|
|
|
|
| Mild persistent |
21 (22%) |
_ |
_ |
_ |
_ |
| Moderate persistent |
36 (38.3%) |
|
|
|
|
| Severe persistent |
37 (39.3%) |
|
|
|
|
| Atopy |
|
|
|
|
|
| Atopic |
67 (71.3%) |
|
_ |
_ |
_ |
| Non atopic |
27 (28.7%) |
90 (100%) |
|
|
|
| Passive smoking exposure |
39 (41.5%) |
28 (31.1%) |
0.168 |
_ |
_ |
| GSTT1 |
|
|
|
|
|
| Null |
82 (87.2% |
88 (97.8%) |
|
|
|
| Present |
12 (12.8%) |
2 (2.2%) |
0.007* |
0.683 |
0.034-0.715 |
| GSTM1 |
|
|
|
|
|
| Null |
47 (50%) |
55 (61.1%) |
|
|
|
| Present | 47 (50%) | 35 (38.9%) | 0.130 | 1.000 | 0.539-1.857 |
ªData are expressed as no. (%) of patients unless otherwise indicated.
*P-value less than 0.05 is considered statistically significant.
**FEV1: forced expiratory volume in 1 second, ***FVC: forced vital capacity.