Table 2.
Yield, enantioselectivity, and diastereoselectivity of stilbene oxide from benzaldehyde and benzaldehyde tosylhydrazone salt by using sulfides 1, 5, and 6
| Entry | Sulfide | Yield, %* | Trans/cis† | ee %‡ |
|---|---|---|---|---|
| 1 | 1 | 87 | >98:2 | 94 (R, R) |
| 2 | 6 | 80 | >98:2 | 86 (R, R) |
| 3 | 5 | 83 | >98:2 | 78 (R, R) |
Yield of isolated product.
Determined by 1H NMR spectroscopy of crude reaction mixture.
Determined by chiral HPLC with a Chiralcel OD column.
