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. 2014 Mar 4;110(7):1681–1687. doi: 10.1038/bjc.2014.109

Table 4. Uptake of tamoxifen in various clinical situations.

Type of clinical situation Uptake (%) Reference
Non-trial, non-BRCA1/2
Surgical practice—4 surgeons 2/47 (4.7) Port et al, 2001
Post-biopsy. Referred to general practice 1/89 (1.1) Taylor and Taguchi, 2005
Referred to surgical service 57/137 (42.0) Tchou et al, 2004
High-risk clinic 37/158 (29.0) Bober et al, 2004
High-risk clinic 15/48 (31.0) Layeequr Rahman and Crawford, 2009
High-risk clinic 136/1279 (10.6) Donnelly et al—this study
Health-care systems 3/652 (0.5) Fagerlin et al, 2010
Population (US) 2000 27/10 601(0.25) Waters et al, 2010
2005 8/10 690 (0.08) Waters et al, 2010
2010
32/9 906 (0.32)
Waters et al, 2012
Non-trial, BRCA1/2
International study 76/1135 (5.5) Metcalfe et al, 2008
Multicentre study (Canada) 17/270 (6.0) Metcalfe et al, 2007
High-risk clinic
7/170 (4.1)
Donnelly et al—this study
Trial recruitment
IBIS-I 32/278 (11.5) Evans et al, 2001
IBIS-I 273/2278 (12.0) Evans et al, 2010
STAR 35/158 (27.0) Bober et al, 2004
STAR 19 747/91 325 (21.6) McCaskill-Stevens et al, 2013
P1 13 954/57 641 (24.2) Fisher et al, 2005

Abbreviations: IBIS-I=International Breast Cancer Intervention Study I; STAR= Study of Tamoxifen and Raloxifene.