Table 4. Uptake of tamoxifen in various clinical situations.
Type of clinical situation | Uptake (%) | Reference |
---|---|---|
Non-trial, non-BRCA1/2 | ||
Surgical practice—4 surgeons | 2/47 (4.7) | Port et al, 2001 |
Post-biopsy. Referred to general practice | 1/89 (1.1) | Taylor and Taguchi, 2005 |
Referred to surgical service | 57/137 (42.0) | Tchou et al, 2004 |
High-risk clinic | 37/158 (29.0) | Bober et al, 2004 |
High-risk clinic | 15/48 (31.0) | Layeequr Rahman and Crawford, 2009 |
High-risk clinic | 136/1279 (10.6) | Donnelly et al—this study |
Health-care systems | 3/652 (0.5) | Fagerlin et al, 2010 |
Population (US) 2000 | 27/10 601(0.25) | Waters et al, 2010 |
2005 | 8/10 690 (0.08) | Waters et al, 2010 |
2010 |
32/9 906 (0.32) |
Waters et al, 2012 |
Non-trial, BRCA1/2 | ||
International study | 76/1135 (5.5) | Metcalfe et al, 2008 |
Multicentre study (Canada) | 17/270 (6.0) | Metcalfe et al, 2007 |
High-risk clinic |
7/170 (4.1) |
Donnelly et al—this study |
Trial recruitment | ||
IBIS-I | 32/278 (11.5) | Evans et al, 2001 |
IBIS-I | 273/2278 (12.0) | Evans et al, 2010 |
STAR | 35/158 (27.0) | Bober et al, 2004 |
STAR | 19 747/91 325 (21.6) | McCaskill-Stevens et al, 2013 |
P1 | 13 954/57 641 (24.2) | Fisher et al, 2005 |
Abbreviations: IBIS-I=International Breast Cancer Intervention Study I; STAR= Study of Tamoxifen and Raloxifene.