Table 7. 3-I-ZrMS as a storable chiral Lewis acid.
| Storage time, week | 0 | 2 | 6 | 13 |
|---|---|---|---|---|
| Yield, % | Quant. | Quant. | Quant. | Quant. |
| syn/anti | 5/95 | 5/95 | 5/95 | 5/95 |
| ee, % (anti) | 99 | 99 | 99 | 99 |
The results of the reaction of 5a with 2f using (R)-3-I-ZrMS (10 mol %) and PrOH (80 mol %). Quant., quantitative.