Table 1. Characteristics of 61 213 colorectal cancer patients by diabetes statusa.
|
Diabetes |
||||
|---|---|---|---|---|
| No diabetes | Total no. (%) | Without complication | With complicationb | |
| All patients | 46 400 | 14 813 (24.2) | 12 298 (20.1) | 2515 (4.1) |
|
Age (year) | ||||
| 65–74 | 16 708 (36) | 5965 (40) | 4912 (34) | 1053 (42) |
| 75–84 | 20 744 (44) | 6682 (45) | 5556 (45) | 1126 (45) |
| 85+ | 8948 (19) | 2166 (15) | 1830 (15) | 336 (13) |
| Sex (female, %) | 25 762 (56) | 7785 (53) | 6501 (53) | 1284 (51) |
|
Race | ||||
| White | 40 650 (88) | 12 167 (82) | 10 206 (83) | 1961 (78) |
| Black | 3411 (7) | 1779 (12) | 1383 (11) | 396 (16) |
| American Indian/Alaska Native | 115 (0) | 61 (0) | 47 (0) | >11 (∼) |
| Asian or Pacific Islander | 2025 (4) | 754 (5) | 616 (5) | 138 (6) |
| Unknown | 199 (0) | 52 (0) | 46 (0) | <11 (∼) |
|
Marital status | ||||
| Single (never married) | 3623 (8) | 1169 (8) | 954 (8) | 215 ((9) |
| Married | 22 715 (49) | 7151 (48) | 6010 (49) | 1141 (45) |
| Separated | 270 (1) | 121 (1) | 101 (1) | 20 (1) |
| Divorced | 2881 (6) | 1003 (7) | 807 (7) | 196 (8) |
| Widowed | 14 881 (32) | 4711 (32) | 3871 (32) | 840 (33) |
| Unknown | 2030 (4) | 658 (4) | 555 (6) | 103 (4) |
|
Median Income | ||||
| Lowest quartile | 11 092 (24) | 4210 (28) | 3436 (28) | 774 (31) |
| Second quartile | 11 483 (25) | 3823 (26) | 3193 (27) | 630 (25) |
| Third quartile | 11 666 (25) | 3644 (25) | 3056 (25) | 588 (23) |
| Highest quartile | 12 159 (26) | 3136 (25) | 2613 (21) | 523 (21) |
|
No. of comorbidities | ||||
| 0 | 37 348 (81) | 9624 (65) | 8502 (69) | 1122 (45) |
| 1 | 5323 (12) | 2313 (16) | 1855 (15) | 458 (18) |
| ⩾2 | 3729 (8) | 2876 (19) | 1941 (16) | 935 (37) |
|
Cancer site at diagnosis | ||||
| Colon | 34 851(75) | 11 632 (79) | 9598 (78) | 2034 (81) |
| Rectum | 11 549 (25) | 3181 (21) | 2700 (22) | 481 (19) |
|
Cancer stage | ||||
| Localised | 20 088 (43) | 6478 (44) | 5336 (43) | 1142 (45) |
| Regional | 17 520 (38) | 5758 (39) | 4822 (39) | 936 (37) |
| Distant | 6679 (14) | 1921 (13) | 1617 (13) | 304 (12) |
| Unknown | 2113 (5) | 656 (4) | 523 (4) | 133 (5) |
|
Grade | ||||
| Grade I: well differentiated | 4132 (9) | 1335 (9) | 1097 (9) | 238 (10) |
| Grade II: moderately differentiated | 28 262 (61) | 9258 (63) | 7723 (63) | 1535 (61) |
| Grade III: poorly differentiated | 7762 (17) | 2403 (16) | 1981 (16) | 422 (17) |
| Grade IV: undifferentiated | 659 (1) | 205 (1) | 171 (1) | 34 (1) |
| Unknown | 5585 (12) | 1612 (11) | 1326 (11) | 286 (11) |
|
Cancer-direct surgery | ||||
| No | 5099 (11) | 1533 (10) | 1237 (10) | 296 (12) |
| Yes | 40 915 (88) | 13 158 (89) | 10 967 (89) | 2191 (87) |
| Unknown | 386 (1) | 122 (1) | 94 (1) | 28 (1) |
|
Radiation therapy | ||||
| No | 41 187 (89) | 13 395 (9) | 11 089 (90) | 2306 (92) |
| Yes | 4628 (10) | 1214 (8) | 1043 (9) | 171 (7) |
| Unknown | 585 (1) | 204 (1) | 166 (1) | 38 (2) |
|
Chemotherapy | ||||
| Yes | 4055 (9) | 1338 (9) | 1161 (9) | 177 (7) |
a
All tests are significant at P<0.05 between two groups (non-diabetes vs diabetes) or among three groups (non-diabetes, diabetes without complication and diabetes with complication).
b
There are n=6 cases of Unknown race with diabetes and complications. To comply with the SEER-Medicare rules the cell sizes were suppressed for confidentiality reasons as per the SEER-Medicare data usage agreement.