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. 2014 Feb 25;110(7):1698–1704. doi: 10.1038/bjc.2014.95

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Copyright © 2014 Cancer Research UK

From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Pancytokeratin immunohistochemistry section of pancreatic cancer from patient 7 who underwent a Whipple's pancreaticoduodenectomy 5 weeks after PDT. The patient received radiotherapy 5 months before PDT, causing fibrosis over a wide part of the gland in addition to that inherent to pancreatic adenocarcinomas. However, there is a clearly identifiable central area in this section of the tumour with a markedly reduced number of cells, compared with the surrounding tumour. This corresponds to the PDT-treated area.