Table 1. Details of patients and treatments.
| Patient number | Sex/age | Baseline tumour diam. (cm) | Total energy (J) | Mean necrosis diameter on day 5 CT (cm) | Necrosis volume on day 5 CT (cm3) |
|---|---|---|---|---|---|
| 1 |
M/59 |
4.0 |
5 |
0 |
0 |
| 2 |
M/76 |
4.4 |
5 |
0 |
0 |
| 3 |
M/62 |
N/Aa |
5 |
0 |
0 |
| 4 |
F/54 |
3.8 |
10 |
1.4 |
0.96 |
| 5 |
M/63 |
2.8 |
10 |
0.5 |
0.43 |
| 6 |
M/68 |
4.2 |
10 |
0 |
0 |
| 7 |
M/47 |
3.8 |
20 |
0.5 |
0.34 |
| 8 |
M/54 |
4.0 |
20 |
1.9 |
2.37 |
| 9 |
F/56 |
3.5 |
20 |
1.8 |
0.72 |
| 10 |
F/59 |
N/Aa |
40 |
2.2 |
5.17 |
| 11 |
M/57 |
3.8 |
40 |
2.1 |
2.61 |
| 12 |
M/78 |
6.5 |
40 |
N/A |
N/Ab |
| 13 |
F/69 |
2.0 |
40 |
2.1 |
2.67 |
| 14 |
M/56 |
3.7 |
80 |
3.1 |
5.3 |
| 15 | M/65 | 5.3 | 240 | 4.1 | 23.2 |
Abbreviations: CT=computed tomography; F=female; M=male; PDT=photodynamic therapy.
The diameter of necrosis given is the mean of the extent of necrosis in the x, y, and z planes. All patients were treated with a single optical fibre with a 1-cm diffuser tip except patient 14 (two fibres, each with a 1-cm diffuser tip, 40 J cm−1) and patient 15 (three fibres, each with a 2-cm diffuser tip, 40 J cm−1).
a
In patients 3 and 10, the margins were not well enough defined to measure the tumour size.
b
In patient 12, there was tumour-related necrosis before PDT so the effect of PDT could not be assessed.