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. Author manuscript; available in PMC: 2014 Apr 3.
Published in final edited form as: Oncol Res. 2008;17(5):193–203. doi: 10.3727/096504008786111365

Figure 3.

Figure 3

(I) Photomicrographs of immunohistochemical staining of CYP1A1, 1B1 and 8-OH-dG expression in the buccal pouch of control and experimental animals (20X)

A Overexpression of CYP1A1, 1B1 and 8-OH-dG in the pouch and liver tissues of DMBA treated animals (group 1)

B,C,D Downregulation of CYP1A1, B1 and 8-OH-dG in animals administered DMBA+bLF, DMBA+P-B and DMBA+bLF+P-B treated animals (groups 2, 3 and 4 respectively)

E Normal expression of CYP1A1, B1 and 8-OH-dG in animals groups 5 through 8.

(II) The expression of CYP1A1, 1B1 and 8-OH-dG in the buccal pouch of control and experimental animals (Mean ± SD; n=20)

♠♠ Significantly different from group 8 animals (p< 0.0001)

* Significantly different from group 1 animals (p<0.05)

** Significantly different from group 1 animals (p< 0.001)

*** Significantly different from group 1 animals (p< 0.0001)