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. 2014 Mar 25;11:56. doi: 10.1186/1742-2094-11-56

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Copyright © 2014 Wang et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Aspirin attenuated ionized calcium binding adapter molecule 1 (Iba-1) expression in the ischemic penumbral tissues. Rats received or did not receive aspirin for 7 days before a 90-minute middle cerebral arterial occlusion (MCAO). Brain was harvested 24 hours after the MCAO for immunostaining of Iba-1. (A) Representative immunostaining images. Scale bars = 200 μm. (B) Graphic presentation of the percentage area that is Iba-1-positive stained in the total area of the image. Values presented as mean ± SEM (n = 8). *P < 0.05, compared with sham; ^P < 0.05, compared with MCAO. ASA, acetylsalicylic acid.