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. 2014 Jan 8;5(1):25–45. doi: 10.4338/ACI-2013-08-RA-0057

Table 1.

Information contained in rules for one form of parenteral methotrexate and a formulation of acetaminophen. The most specific rule that applies to the order is applied to generate the alert. Note that some rules for a specific amount (mg) to be given, and others are computed based on body surface area.

Medication Route Rule Conditions
Patient
age range (days)
Patient
weight (kg)
Gestational
age
(days)
Dose range or
maximum dose
for single dose
Methotrexate
25 mg/mL
injection
Intravenous 0 – 4,380 5–30 mg/m2
4,381 – 36,135 5–50 mg/m2
Intrathecal Oral 0 – 120 3 mg
121 – 365 6 mg
366 – 730 8 mg
731 – 1,095 10 mg
1,096 – 3,285 12 mg
3,286 – 36,135 12–15 mg
Acetaminophen
160 mg/5 mL
oral solution
0ral 0–9 196–230 12 mg/kg
231–350 15 mg/kg
10–29 15 mg/kg
30–4379 0–9.999 15 mg/kg
30–4379 10–40 15 mg/kg
30–4379 40.001–100 1000 mg
4380–99,999 1000 mg