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. 2014 Apr 3;2014:bau026. doi: 10.1093/database/bau026

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© The Author(s) 2014. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Comparison of domain assignments by PFAM and 3PFDB+ on 50 reviewed human proteins from UNIPROT. The distribution of sequences under different categories based on clear functional relevance of domain assignments is presented. Functionally relevant is abbreviated as FR. Domain assignments related by PFAM Clan grouping or GO annotations, are marked as ‘Related’. Sequences for which domain assignments were given only by 3PFDB+ or PFAM are indicated as ‘3PFDB+ only’ or ‘PFAM only’. Additional FR domains assigned by 3PFDB+ or PFAM are marked as ‘FR additional domain by 3PFDB+’ or ‘FR additional domain by PFAM’. Assignments with a combination of related and additional domains are subgrouped under ‘Related’ depending on additional assignments by PFAM or 3PFDB+. Related assignments with same number of domains are indicated as ‘Related: Similar number of domains’. The domain assignments which needed further assessments due to insufficient or no annotation (UNIPROT or GO), are grouped under ‘Different (insufficient annotation)’.