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Measurements of circulatory endothelial and endothelial surface layer damage markers in participants with and without loss of renal function. Markers were measured in healthy controls (n=10) and patients with ESRD (n=23), stable KTx (n=12), and IFTA (n=10). (A) Serum angiopoietin-2 (Ang2). (B) Serum soluble thrombomodulin (sTM). (C) Plasma shed syndecan-1. Box plot whiskers indicate 1st and 99th percentiles. *P<0.05; **P<0.01; **P<0.001.
