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. 2014 Mar 27;9(4):654–662. doi: 10.2215/CJN.09720913

Figure 1.

Figure 1.

Renal angina. (A) The renal angina construct. The juxtaposed graphs depict risk of AKI versus decrease in estimated creatinine clearance from baseline (↓eCrCl) and versus increase in the percentage of intensive care unit fluid overload (% ↑ICU FO). There are three risk groups defined for the pediatric intensive care unit population (tranches): very high risk (intubated plus the presence of at least one vasopressor or inotrope), high risk (history of solid organ or bone marrow transplant), and moderate (ICU admission). The construct is created such that less sign of injury (eCrCl change or FO change) is required for the higher risk tranches to fulfill renal angina (solid red slope line). Adapted with permission from Goldstein and Chawla (9). (B) The renal angina index (RAI). On the basis of existing pediatric AKI literature, tiered AKI risk strata were assigned point values for risk and signs of injury. The worse parameter between change in eCrCl from baseline and the percentage of fluid overload (% FO) was used to yield an injury score. The full description of the derivation appears in Supplemental Material A. The resultant RAI score can range from 1 to 40. A cut-off of ≥8 is used to determine renal angina fulfillment.