Table 4.
Performance of the RAI and serum biomarkers for prediction of subsequent severe AKI
| Test | RAI | NGAL | MMP-8 | Ela-2 |
|---|---|---|---|---|
| Sensitivity | 93 (76 to 99) | 90 (72 to 97) | 86 (69 to 95) | 90 (73 to 97) |
| Specificity | 36 (33 to 37) | 34 (28 to 42) | 33 (30 to 34) | 44 (42 to 46) |
| PPV | 18 (15 to 19) | 18 (12 to 25) | 16 (13 to 18) | 20 (16 to 21) |
| NPV | 97 (90 to 99) | 97 (87 to 99) | 94 (87 to 98) | 97 (91 to 99) |
| AUC-ROC | 0.80 (0.75 to 0.86) | 0.72 (0.63 to 0.82) | 0.68 (0.59 to 0.78) | 0.72 (0.62 to 0.82) |
Data are presented as the percentage (95% confidence interval). A RAI score of ≥8 is considered fulfillment of renal angina. The fulfillment of renal angina on day 0 was compared with the presence of AKI on day 3 of admission for the sensitivity, specificity, PPV, and NPV. The absolute value of the RAI (range, 1–40) was used to derive the AUC-ROC.