Table 3.
Breast-Feeding Recommendations for Acute Migraine Treatment
| Drug | Hale Lactation Rating | Drugs in Pregnancy and Lactation Briggs Category |
|---|---|---|
| Simple analgesics and non-steroidal anti-inflammatory drugs | ||
| Acetaminophen | L1 | Compatible |
| Aspirin | L3 | Potential toxicity |
| Diclofenac | L2 | Probably compatible |
| Ibuprofen | L1 | Compatible |
| Indomethacin | L3 | Probably compatible |
| Ketorolac | L2 | Probably compatible |
| Naproxen | L3 or L4 | Probably compatible |
| Migraine-specific medications | ||
| Almotriptan | L3 | Probably compatible |
| Eletriptan | L2 | Compatible |
| Frovatriptan | L3 | Probably compatible |
| Naratriptan | L3 | Probably compatible |
| Rizatriptan | L3 | Probably compatible |
| Sumatriptan | L3 | Probably compatible |
| Zolmitriptan | L3 | Probably compatible |
| Dihydroergotamine | L4 | Contraindicated |
| Ergotamine | L4 | Contraindicated |
| Antiemetics and neuroleptics | ||
| Metoclopramide | L2 | Potential toxicity |
| Ondansetron | L2 | Probably compatible |
| Prochlorperazine | L3 | Potential toxicity |
| Promethazine | L2 | Probably compatible |
| Chlorpromazine | L3 | Potential toxicity |
| Haloperidol | L2 | Potential toxicity |
| Olanzapine | L2 | Potential toxicity |
| Opioids | ||
| Butorphanol | L2 | Probably compatible |
| Codeine | L3 | Potential toxicity |
| Hydrocodone | L3 | Potential toxicity |
| Hydromorphone | L3 | Probably compatible |
| Meperidine | L2 | Compatible |
| Oxycodone | L3 | Probably compatible |
| Others | ||
| Butalbital | L3 | Potential toxicity |
| Caffeine | L2 | Compatible |
| Isometheptene | L3 | Probably compatible |
| Lidocaine | L2 | Probably compatible |
| Dexamethasone | L3 | Probably compatible |
| Prednisone | L2 | Compatible |
| Diphenhydramine | L2 | Probably compatible |