Table 1.
Demographic and clinical features of patients with nonalcoholic fatty liver disease and controls n (%)
| NAFLD patients (n = 390) | Controls (n = 409) | P value | |
| BMI (kg/m2) | 24.83 ± 2.82 | 22.18 ± 4.02 | 0.000a |
| Waist (cm) | 84.18 ± 8.19 | 75.78 ± 9.13 | 0.000a |
| Hypertension | 89 (22.8) | 42 (10.3) | 0.000c |
| T2DM | 87 (22.3) | 36 (8.8) | 0.000c |
| ALT (U/L) | 44.86 ± 40.16 | 34.32 ± 22.27 | 0.000a |
| AST (U/L) | 33.40 ± 32.60 | 32.60 ± 36.42 | 0.762 |
| GGT (U/L) | 43.82 ± 42.17 | 34.00 ± 26.92 | 0.000a |
| FPG (mmol/L) | 6.03 ± 1.77 | 5.18 ± 0.82 | 0.357 |
| UA (mmol/L) | 326.03 ± 105.24 | 332.88 ± 104.74 | 0.000a |
| TG (mmol/L) | 2.91 ± 1.43 | 2.26 ± 1.55 | 0.000a |
| TC (mmol/L) | 5.17 ± 1.00 | 4.77 ± 0.85 | 0.000a |
| HDL (mmol/L) | 1.71 ± 0.99 | 2.38 ± 2.36 | 0.000a |
| LDL (mmol/L) | 4.28 ± 3.44 | 3.17 ± 1.78 | 0.000a |
| FINS (μU/mL) | 6.27 ± 1.34 | 5.51 ± 1.01 | 0.000a |
| HOMA-IR (U) | 1.67 ± 0.62 | 1.27 ± 0.32 | 0.000a |
Data are expressed as mean ± SD,
a
P < 0.05 vs controls, by unpaired Student’s t test;
c
P < 0.05 vs controls, by χ2 test. Body mass index (BMI) was calculated as body weight (kg)/height (m2); ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: γ-glutamyltransferase; FPG: Fasting blood glucose; UA: uric Acid; TC: Total cholesterol; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; FINS: Fasting blood insulin; NAFLD: Nonalcoholic fatty liver disease; TG: Triglyceride; HOMA-IR: Homeostatic model assessment of insulin resistance.