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. 2014 Apr 7;20(13):3655–3662. doi: 10.3748/wjg.v20.i13.3655

Table 3.

Odds ratios for nonalcoholic fatty liver disease according to apolipoprotein C3 and patatin-like phospholipase domain-containing protein 3 genotypes and alleles in the study population

Unadjusted model
Adjusted model
OR (95%CI) P value OR (95%CI) P value
APOC3 gene
-455TT 1 1
-455TC + CC 0.96 (0.70-1.32 ) 0.82 1.06 (0.72-1.57 ) 0.76
-482CC 1 1
-482CT + TT 0.90 (0.66-1.24 ) 0.52 1.00 (0.68-1.48 ) 1.00
PNPLA3 gene
CC 1 1
CG + GG 5.77 (4.03-8.27) 0.00 3.70 (2.44-5.60) 0.00

-455C vs T: OR (95%CI) = 1.00 (0.82-1.22): -482C vs T: OR (95%CI) = 0.99 (0.81-1.21); PNPLA3G vs C: OR (95%CI) = 2.00 (1.80-2.23). The multiple logistic regression model was adjusted for age, gender, body mass index, waist, weight and presence of hypertension and T2DM.