Table 3.
Prevalence of atopic dermatitis (AD) and filaggrin gene (FLG) loss-of-function mutations in patients and controls
| Controls | Patients | ||||||
|---|---|---|---|---|---|---|---|
| FLG loss-of-function mutation | FLG loss-of-function mutation | ||||||
| No | Yes | Total | No | Yes | Total | ||
| History of ADa | No | 237 (75.2%) | 19 (6.0%) | 256 (81.3%) | 301 (52.6%) | 36 (6.3%) | 337 (58.9%) |
| Yes | 51 (16.2%) | 8 (2.5%) | 59 (18.7%) | 182 (31.8%) | 53 (9.3%) | 235 (41.1%) | |
| Total | 288 (91.4%) | 27 (8.6%) | 315 (100%) | 483 (84.4%) | 89 (15.6%) | 572 (100%) | |
a
AD was defined by current or past flexural eczema